Aseptic Area


  • Ceiling : Smooth surface, easy to clean, Epoxy or vinyl coating
  • Personnel should enter the aseptic area only through an air lock.
  • Material should be transferred through Pass-box sterilizers.
  • Prior filling, area should be sterilized with gaseous disinfectant like formaldehyde.
  • Surface should be sterilized using UV lamp.
  • HEPA (High efficiency Particulate Air Filter: 99.97 % efficiency, 0.3mcM or larger particles must be retained) filter should be placed in order to control particles.
  • Air handling unit (AHU) to control temperature and humidity.
  • Laminar Air Flow: 90 +- 20 ft/min with parallel flow.
  • DOP test: Dioctylphalate smoke used to measure efficiency of HEPA filter by anemometer.

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